Fig. 1 · Structure
Documents & Downloads
GYKI 52466
AMPA/Kainate Receptor Antagonist
GYKI 52466 is a selective, noncompetitive antagonist of AMPA and kainate receptors, demonstrating IC50 values of 7.5 µM and 11 µM, respectively. This compound exhibits good blood-brain barrier permeability and has been shown to possess anticonvulsant properties. GYKI 52466 is applicable in research related to neurological disorders, including Parkinson's disease.
In Stock
Free Aliquoting for Your Order
Tell us your preferred amount per vial. We’ll confirm the options.
Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Antagonist |
| CAS Number | 102771-26-6 |
| Applications | AMPA/Kainate Receptor Antagonist |
| Formula | C17H15N3O2 |
| Molecular Weight | 293.32 |
| SMILES | NC1=CC=C(C2=NN=C(C)CC3=CC4=C(OCO4)C=C32)C=C1 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.