GZ-389988 is a potent pan-TRK inhibitor that targets TRKA, TRKB, and TRKC with IC50 values of 0.3 nM, 0.1 nM, and 0.5 nM, respectively. It is valuable for the study of NTRK fusion-positive tumors, facilitating research into their biological mechanisms and potential therapeutic strategies. This compound supports the investigation of TRK-related pathways and their role in oncogenesis.
GZ-389988 is a potent pan-TRK inhibitor that targets TRKA, TRKB, and TRKC with IC50 values of 0.3 nM, 0.1 nM, and 0.5 nM, respectively. It is valuable for the study of NTRK fusion-positive tumors, facilitating research into their biological mechanisms and potential therapeutic strategies. This compound supports the investigation of TRK-related pathways and their role in oncogenesis.
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