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H-L-Phe(4-NH-Poc)-OH hydrochloride

Azide Compound

H-L-Phe(4-NH-Poc)-OH hydrochloride is an azide-containing reagent that serves as a modified phenylalanine analogue in protein and peptide biosynthesis. It facilitates copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions, making it suitable for click chemistry applications. Additionally, the propargyloxycarbonyl (Poc) group acts as a versatile protecting group for amines and hydroxy functions, providing stability under various conditions. Deprotection can be achieved using transition metals such as cobalt or palladium, enhancing its utility in organic synthesis and bioconjugation studies.

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Specifications

Manufacturer	Adooq Bioscience
CAS Number	2737202-66-1
Applications	Azide Compound
Formula	C₁₃H₁₅ClN₂O₄
Molecular Weight	298.72
SMILES	OC([C@@H](N)CC1=CC=C(C=C1)NC(OCC#C)=O)=O.Cl

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.