Fig. 1 · Structure
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h-NTPDase-IN-2
h-NTPDase Inhibitor
h-NTPDase-IN-2 is a potent pan-inhibitor of human NTPDases, demonstrating IC50 values of 0.35 μM for h-NTPDase1, 4.81 μM for h-NTPDase2, 37.73 μM for h-NTPDase3, and 10.32 μM for h-NTPDase8. This compound is utilized in biochemical research to elucidate the role of NTPDases in various physiological and pathological processes. Its inhibitory properties make it a valuable tool for investigating nucleotide signaling pathways and developing targeted therapies.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 2939933-03-4 |
| Applications | h-NTPDase Inhibitor |
| Formula | C19H16N4S |
| Molecular Weight | 332.42 |
| SMILES | CN(CC1=CC=CC=C1)C2=C3SC=C(C4=CC=NC=C4)C3=NC=N2 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.