Fig. 1 · Structure
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HA-966 hydrochloride
iGluR Antagonist
HA-966 hydrochloride is a glycine site antagonist of the NMDA receptor, functioning as a non-competitive blocker of NMDA-mediated responses. This compound effectively inhibits the potentiation of NMDA activity by glycine, thereby demonstrating its role in modulating synaptic transmission. HA-966 hydrochloride is valuable for research applications targeting glutamatergic signaling and studying the pharmacological properties associated with neuropsychiatric disorders.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Antagonist |
| CAS Number | 42585-88-6 |
| Applications | iGluR Antagonist |
| Formula | C4H9ClN2O2 |
| Molecular Weight | 152.58 |
| SMILES | O=C1N(O)CCC1N.Cl |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.