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Halenaquinone

Phosphatidylinositol 3-kinase Iinhibitor

Halenaquinone is a phosphatidylinositol 3-kinase inhibitor derived from the marine sponge Petrosia alfiani. This compound exhibits significant biological activity by inhibiting RANKL-induced osteoclastogenesis and promoting apoptosis in PC12 neuronal cells. Halenaquinone serves as a valuable reagent in research applications focused on bone diseases and neurodegenerative disorders, facilitating investigations into cellular signaling pathways and the mechanisms of cell death.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	86690-14-4
Applications	Phosphatidylinositol 3-kinase Iinhibitor
Formula	C₂₀H₁₂O₅
Molecular Weight	332.31
SMILES	O=C1CC[C@@](C2=C3OC=C21)(C)C4=C(C3=O)C=C(C(C=CC5=O)=O)C5=C4

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.