Fig. 1 · Structure
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Harmalol hydrochloride
Cytochrome P453 Substrate
Harmalol hydrochloride is a beta carboline alkaloid that serves as a substrate for cytochrome P450 enzymes. It notably inhibits the dioxin-mediated induction of CYP1A1, affecting both transcriptional and posttranslational processes. Additionally, Harmalol hydrochloride demonstrates antioxidant activity and effectively scavenges hydroxyl radicals, making it a valuable reagent for studies involving oxidative stress and enzyme regulation.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Substrate |
| CAS Number | 6028-07-5 |
| Applications | Cytochrome P453 Substrate |
| Formula | C12H13ClN2O |
| Molecular Weight | 236.70 |
| SMILES | CC1=NCCC2=C1NC3=C2C=CC(O)=C3.[H]Cl |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.