Harmine

Catalog No.: A17316

Harmine

Harmine Chemical Structure

CAS NO. 442-51-3

Harmine, also known as telepathine, is a fluorescent harmala alkaloid belonging to the beta-carboline family of compounds. It occurs in a number of different plants, most notably the Middle Eastern plant harmal or Syrian rue (Peganum harmala) and the South American vine Banisteriopsis caapi (also known as "yage" or "ayahuasca"). Harmine reversibly inhibits monoamine oxidase A (MAO-A), an enzyme which breaks down monoamines, making it a RIMA. Harmine selectively binds to MAO-A but does not inhibit the variant MAO-B.

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500 mg
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Biological Activity

Harmine, also known as telepathine, is a fluorescent harmala alkaloid belonging to the beta-carboline family of compounds. It occurs in a number of different plants, most notably the Middle Eastern plant harmal or Syrian rue (Peganum harmala) and the South American vine Banisteriopsis caapi (also known as "yage" or "ayahuasca"). Harmine reversibly inhibits monoamine oxidase A (MAO-A), an enzyme which breaks down monoamines, making it a RIMA. Harmine selectively binds to MAO-A but does not inhibit the variant MAO-B.
In vitro DMSO 42 mg/mL (197.87 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 47.11 mL 235.57 mL 471.14 mL
0.5 mM 9.42 mL 47.11 mL 94.23 mL
1 mM 4.71 mL 23.56 mL 47.11 mL
5 mM 0.94 mL 4.71 mL 9.42 mL

*The above data is based on the productmolecular weight 212.252. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A17316
CAS No. 442-51-3
Formula C13H12N2O
M. Wt 212.252
Purity >98%
Synonyms Harmine; telepathine; Yageine; Yajeine; Banisterine; Leucoharmine.
SMILES CC1=NC=CC2=C1NC3=C2C=CC(OC)=C3
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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