Harzianoside B

Catalog No.: A65286
NO Synthase Inhibitor
Harzianoside B is a diterpene aminoglycoside known for its role as a nitric oxide (NO) synthase inhibitor. It effectively reduces NO production, demonstrating an IC50 value near the maximum tested concentration of 100 µM in RAW 264.7 macrophage cells. This compound is valuable for research into anti-inflammatory mechanisms and therapeutic applications.
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5mg
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50mg
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Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionHarzianoside B is a diterpene aminoglycoside known for its role as a nitric oxide (NO) synthase inhibitor. It effectively reduces NO production, demonstrating an IC50 value near the maximum tested concentration of 100 µM in RAW 264.7 macrophage cells. This compound is valuable for research into anti-inflammatory mechanisms and therapeutic applications.
Product Information
Catalog NumA65286
FormulaC28H45NO7
Molecular Weight507.66
CAS Number3075431-10-3
SMILESOC/C(C[C@H](O[C@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1NC(C)=O)/C=C(C)/CC2)=C\C[C@H]3C(C)(C)C2=C(C)CC3
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