Fig. 1 · Structure
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HB007
SUMO1 Degrader
HB007 is a small ubiquitin-related modifier 1 (SUMO1) degrader that facilitates the ubiquitination and subsequent proteasomal degradation of SUMO1 proteins. This compound has demonstrated the ability to reduce tumor growth in vivo, making it a valuable tool for cancer research. HB007 is applicable in studies related to brain, breast, colon, and lung cancers, providing insights into the role of SUMOylation in tumorigenesis.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Degrader |
| CAS Number | 2387821-46-5 |
| Applications | SUMO1 Degrader |
| Formula | C15H9ClN4OS |
| Molecular Weight | 328.78 |
| SMILES | N#CC1=CC2=C(N=C(NC(NC3=CC(Cl)=CC=C3)=O)S2)C=C1 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.