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HBV/HDV-IN-1

PD-1/PD-L1 Inhibitor

HBV/HDV-IN-1 is a potent inhibitor of PD-1/PD-L1 interactions, demonstrating EC50 values of 8 nM for T cell activation and 35 nM for PD-L1 internalization. This compound is essential for investigating the role of immune checkpoint modulation in hepatitis B virus (HBV) and hepatitis D virus (HDV) infections. Its ability to enhance T cell responses makes it valuable for research in immunotherapy and viral pathogenesis.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	3034161-55-9
Applications	PD-1/PD-L1 Inhibitor
Formula	C₃₈H₄₂Cl₂N₈O₅
Molecular Weight	761.70
SMILES	O=C(NC1=CC=CC(C2=NC=CC(C3=NC(OC)=C(CNC[C@H](CC4)NC4=O)C=C3)=C2Cl)=C1Cl)C5=NC=C(CNC6CCN(C(C)=O)CC6)C(OC)=C5

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.