HBV/HDV-IN-1 is a potent inhibitor of PD-1/PD-L1 interactions, demonstrating EC50 values of 8 nM for T cell activation and 35 nM for PD-L1 internalization. This compound is essential for investigating the role of immune checkpoint modulation in hepatitis B virus (HBV) and hepatitis D virus (HDV) infections. Its ability to enhance T cell responses makes it valuable for research in immunotherapy and viral pathogenesis.
HBV/HDV-IN-1 is a potent inhibitor of PD-1/PD-L1 interactions, demonstrating EC50 values of 8 nM for T cell activation and 35 nM for PD-L1 internalization. This compound is essential for investigating the role of immune checkpoint modulation in hepatitis B virus (HBV) and hepatitis D virus (HDV) infections. Its ability to enhance T cell responses makes it valuable for research in immunotherapy and viral pathogenesis.
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