Fig. 1 · Structure
Documents & Downloads
hCA I-IN-1
hCA I Inhibitor
hCA I-IN-1 is a potent inhibitor of human carbonic anhydrase I (hCA I), exhibiting a Ki value of 38.3 nM against this target. It demonstrates varying inhibition against other isoforms, including hCA II, hCA IX, and hCA XII with Ki values of 716.4 nM, 940.1 nM, and 192.8 nM, respectively. This compound is valuable for research applications aimed at understanding the role of carbonic anhydrases in physiological and pathological processes, particularly in cancer research and metabolic disorders.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 2417232-26-7 |
| Applications | hCA I Inhibitor |
| Formula | C27H23N5O4S |
| Molecular Weight | 513.57 |
| SMILES | COC1=CC=CC(C(/C=C/C2=CN(C3=CC=CC=C23)CC4=CN(N=N4)C5=CC=C(C=C5)S(N)(=O)=O)=O)=C1 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.