Fig. 1 · Structure
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hCAI/II-IN-1
hCA I/II Inhibitor
hCAI/II-IN-1 is a potent inhibitor of human carbonic anhydrases I and II, demonstrating IC50 values of 0.047 µM and 0.024 µM, respectively. This compound exhibits significant biological activity by effectively hindering the enzymatic function of these important targets, which are implicated in various physiological processes and disease states. hCAI/II-IN-1 is valuable for research applications focused on studying carbonic anhydrase-related pathways and developing therapeutic strategies for conditions such as glaucoma, cancer, and metabolic disorders.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 2422028-82-6 |
| Applications | hCA I/II Inhibitor |
| Formula | C18H29N5O3S3 |
| Molecular Weight | 459.65 |
| SMILES | CN(CCCN1CCN(CC1)C(SCC(NC2=CC=C(C=C2)S(N)(=O)=O)=O)=S)C |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.