hCAI/II-IN-6 is a selective inhibitor of human carbonic anhydrase isoforms II and VII, exhibiting Ki values of 4.9 nM and 6.5 nM, respectively. This compound demonstrates pronounced anticonvulsant activity and provides protective effects against maximal electroshock (MES) seizures in vivo. hCAI/II-IN-6 serves as a valuable tool for research studies focusing on epilepsy and related neurophysiological conditions.
hCAI/II-IN-6 is a selective inhibitor of human carbonic anhydrase isoforms II and VII, exhibiting Ki values of 4.9 nM and 6.5 nM, respectively. This compound demonstrates pronounced anticonvulsant activity and provides protective effects against maximal electroshock (MES) seizures in vivo. hCAI/II-IN-6 serves as a valuable tool for research studies focusing on epilepsy and related neurophysiological conditions.
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