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hCAI/II/XII-IN-1

Human Carbonic Anhydrase Inhibitors

hCAI/II/XII-IN-1 is a potent inhibitor of human carbonic anhydrases I, II, and XII, exhibiting Ki values of 78.5 nM, 9.1 nM, 605 nM, 7.7 nM, and 3.7 nM for each isoform respectively. This compound demonstrates significant biological activity that can be leveraged in research applications targeting metabolic regulation, pH balance, and various diseases such as glaucoma and cancer. Its specificity and efficacy make it a valuable tool for investigating the role of carbonic anhydrases in physiological and pathological processes.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	100142-87-8
Applications	Human Carbonic Anhydrase Inhibitors
Formula	C₁₂H₁₂N₂O₂S
Molecular Weight	248.30
SMILES	O=S(C1=CC=C(C2=CC=C(N)C=C2)C=C1)(N)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.