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hCAII-IN-3

hCA Inhibitor

hCAII-IN-3 is a potent inhibitor of human carbonic anhydrases, demonstrating Ki values of 403.8 nM for hCA I, 5.1 nM for hCA II, 10.2 nM for hCA IX, and 5.2 nM for hCA XII. This compound has been shown to possess significant anticancer activity, making it a valuable tool for exploring therapeutic strategies targeting carbonic anhydrase pathways in cancer research. Its selective inhibition profile supports investigations into various biological processes influenced by carbonic anhydrases.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	2770927-76-7
Applications	hCA Inhibitor
Formula	C₁₇H₂₁N₃O₃S
Molecular Weight	347.43
SMILES	NS(=O)(C1=CC=C(C=C1)NCC/C(C2=CC=CC=C2)=N/CCO)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.