Fig. 1 · Structure
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hCAII-IN-4
hCA II Inhibitor
hCAII-IN-4 is a potent inhibitor of human carbonic anhydrase II (hCA II) with an IC50 of 7.78 μM. Additionally, hCAII-IN-4 exhibits inhibitory activity against β-glucuronidase with an IC50 of 773.9 μM. This compound is useful for studies investigating hCA II-related pathways and potential therapeutic applications in conditions where hCA II dysregulation occurs.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 2816080-18-7 |
| Applications | hCA II Inhibitor |
| Formula | C31H23NO9 |
| Molecular Weight | 553.52 |
| SMILES | O=C(C(C1C2=CC=CC=C2OCC(C3=O)=CC4=C(O3)C=CC=C4)=C(N)OC(C5=C(O6)C=C(O)C=C5)=C1C6=O)OCC |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.