hCAIX-IN-10 is a selective inhibitor of carbonic anhydrases IX and XII, exhibiting Ki values of 61.5 nM and 586.8 nM for hCA IX and hCA XII, respectively. As transmembrane isoforms, hCA IX and hCA XII are recognized as key biomarkers for various tumors. The inhibition of these enzymes is pivotal in research focused on tumor progression, acid-base balance, and potential therapeutic strategies targeting cancer metabolism.
hCAIX-IN-10 is a selective inhibitor of carbonic anhydrases IX and XII, exhibiting Ki values of 61.5 nM and 586.8 nM for hCA IX and hCA XII, respectively. As transmembrane isoforms, hCA IX and hCA XII are recognized as key biomarkers for various tumors. The inhibition of these enzymes is pivotal in research focused on tumor progression, acid-base balance, and potential therapeutic strategies targeting cancer metabolism.
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