hCAIX-IN-18 is a potent inhibitor of carbonic anhydrase (CA), demonstrating inhibition constants (Kis) of 3.5 nM, 9.4 nM, 43.0 nM, and 8.2 nM for human carbonic anhydrases I, II, IX, and XII, respectively. This compound is particularly relevant for cancer research, where it may affect tumor growth and metabolism through the modulation of CA activity. Its specificity and efficacy make it a valuable tool for investigating the role of carbonic anhydrases in various pathological conditions.
hCAIX-IN-18 is a potent inhibitor of carbonic anhydrase (CA), demonstrating inhibition constants (Kis) of 3.5 nM, 9.4 nM, 43.0 nM, and 8.2 nM for human carbonic anhydrases I, II, IX, and XII, respectively. This compound is particularly relevant for cancer research, where it may affect tumor growth and metabolism through the modulation of CA activity. Its specificity and efficacy make it a valuable tool for investigating the role of carbonic anhydrases in various pathological conditions.
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