Fig. 1 · Structure
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HCAIX-IN-2
Carbonic Anhydrase Inhibitor
HCAIX-IN-2 is a selective inhibitor of carbonic anhydrase, specifically targeting isoforms hCA IX and hCA XII with Ki values of 24.6 nM and 45.3 nM, respectively. This compound exhibits significant biological activity in modulating carbonic anhydrase activity, making it a valuable tool in cancer research and therapeutic development. Its inhibitory effects may provide insights into the role of carbonic anhydrases in tumor progression and offer potential avenues for treatment strategies.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 2389034-45-9 |
| Applications | Carbonic Anhydrase Inhibitor |
| Formula | C19H16N8O4S |
| Molecular Weight | 452.45 |
| SMILES | CC1=CC(N2C(C(N/N=C/C3=CC=NC=C3)=O)=NN(C2=N1)C4=CC=C(C=C4)S(N)(=O)=O)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.