Fig. 1 · Structure
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hCAIX-IN-7
hCAIX Inhibitor
hCAIX-IN-7 is a selective inhibitor of human carbonic anhydrase IX (hCAIX), exhibiting remarkable potency with inhibition constants (KIs) of >10000 nM for hCAI and hCAII, 43.0 nM for hCAIV, and 410.6 nM for hCAIX. This compound is crucial for research applications focusing on tumor biology and hypoxia, as hCAIX is highly expressed in various cancer types. hCAIX-IN-7 serves as a valuable tool for investigating therapeutic strategies targeting hCAIX in cancer research.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 2451479-58-4 |
| Applications | hCAIX Inhibitor |
| Formula | C18H12FNO3 |
| Molecular Weight | 309.29 |
| SMILES | O=C(NC1=CC2=C(OC(C=C2)=O)C=C1)/C=C/C3=CC=CC(F)=C3 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.