Fig. 1 · Structure

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hCAIX/VII-IN-1

hCA VII/IX Inhibitor

hCAIX/VII-IN-1 is a potent and selective inhibitor of human carbonic anhydrases VII and IX, exhibiting varying inhibitory activity against additional isoforms. It displays Ki values of 336.2 nM for hCA I, 185.8 nM for hCA II, 1055 nM for hCA IV, 35.6 nM for hCA VII, and 28.0 nM for hCA IX. This compound serves as a valuable tool for research in cancer and neurological disorders, allowing for the exploration of therapeutic strategies targeting these pathways.

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Specifications

Manufacturer Adooq Bioscience
Actions Inhibitor
CAS Number 2990559-21-0
Applications hCA VII/IX Inhibitor
Formula C16H13BFN3O3
Molecular Weight 325.10
SMILES
OB1OCC2=CC=C(C=C12)N3N=NC(COC4=CC=C(C=C4)F)=C3

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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