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hCAIX/XII-IN-12

hCAIX/XII Inhibitor

hCAIX/XII-IN-12 is a potent and highly selective dual inhibitor of human carbonic anhydrases IX and XII, exhibiting Ki values of 8.2 nM and 5.6 nM, respectively. This compound demonstrates significant anti-proliferative activity against colon cancer cells, maintaining efficacy even under hypoxic conditions. hCAIX/XII-IN-12 is suitable for research applications focused on colon cancer treatment and the exploration of its underlying biology.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	4224-84-4
Applications	hCAIX/XII Inhibitor
Formula	C₁₁H₇BrO₄
Molecular Weight	283.07
SMILES	O=C1OC2=C(C(O)=C1C(C)=O)C=C(Br)C=C2

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.