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hCAIX/XII-IN-15

hCAIX/XII Inhibitor

hCAIX/XII-IN-15 is a potent inhibitor of human carbonic anhydrase IX (hCA IX) and XII (hCA XII), exhibiting inhibition constants (Kis) of 0.42 μM and 4.37 μM, respectively. This compound demonstrates pro-apoptotic activity in multiple myeloma cells, making it a valuable tool for studies on cancer biology and therapeutic interventions. Its specificity towards hCA IX and hCA XII positions hCAIX/XII-IN-15 as a significant reagent for research in tumor-associated enzyme inhibition and apoptosis pathways.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	69141-46-4
Applications	hCAIX/XII Inhibitor
Formula	C₁₇H₁₈O₄S
Molecular Weight	318.39
SMILES	O=S(C1=CC=C(C)C=C1)(OC2=CC(C(C)C)=CC=CC2=O)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.