Fig. 1 · Structure
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hCAIX/XII-IN-4
CAIX/XII Inhibitor
hCAIX/XII-IN-4 is a selective inhibitor of the carbonic anhydrases IX (CAIX) and XII (CAXII), exhibiting Ki values of 4.5 nM and 23.6 nM for CAXII and CAIX respectively. This compound demonstrates significant inhibition of carbonic anhydrase activity, making it valuable for research into tumor biology and potential cancer therapies. Its high specificity may also enhance studies focused on the physiological roles of these enzymes in various pathophysiological conditions.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 1119200-33-7 |
| Applications | CAIX/XII Inhibitor |
| Formula | C20H16N2O5 |
| Molecular Weight | 364.35 |
| SMILES | O=C1C=C(C)C2=C(O1)C=C(OCC3=NOC(C4=CC=C(OC)C=C4)=N3)C=C2 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.