hCAIX/XII-IN-5 is a selective inhibitor of carbonic anhydrases IX and XII, demonstrating Ki values of 93.9 nM and 85.7 nM, respectively. This compound exhibits notable anti-proliferative effects on cancer cells, leading to cell cycle delay and the induction of apoptosis. hCAIX/XII-IN-5 is a valuable tool for elucidating the roles of carbonic anhydrases in cancer biology and for developing targeted therapeutic strategies.
hCAIX/XII-IN-5 is a selective inhibitor of carbonic anhydrases IX and XII, demonstrating Ki values of 93.9 nM and 85.7 nM, respectively. This compound exhibits notable anti-proliferative effects on cancer cells, leading to cell cycle delay and the induction of apoptosis. hCAIX/XII-IN-5 is a valuable tool for elucidating the roles of carbonic anhydrases in cancer biology and for developing targeted therapeutic strategies.
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