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hCAIX/XII-IN-6

Arbonic Anhydrase (CA ) Inhibitor

hCAIX/XII-IN-6 is a selective inhibitor of human carbonic anhydrase (CA) isoforms, particularly hCA IX and XII, demonstrating Ki values of 4.1 nM and 7.7 nM, respectively. This compound effectively modulates the activity of other CA isoforms, including hCA I, II, and IV, with varying inhibition potency. hCAIX/XII-IN-6 is valuable for investigating its potential therapeutic applications in conditions such as rheumatoid arthritis (RA), highlighting its relevance in inflammatory research and enzyme regulation studies.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	3031666-31-3
Applications	Arbonic Anhydrase (CA ) Inhibitor
Formula	C₂₆H₂₃N₃O₆S₄
Molecular Weight	601.74
SMILES	O=C(N(CC1=CC=C([N+]([O-])=O)C=C1OC)CCC2=CC=C(S(=O)(N)=O)C=C2)C3=CC=C(C4=CSSC4=S)C=C3

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.