Fig. 1 · Structure
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hCAXII-IN-4
CAXII Inhibitor
hCAXII-IN-4 is a highly selective inhibitor of carbonic anhydrase II (CA XII), demonstrating a potent inhibitory effect with a Ki value of 6.4 nM. This compound is valuable for research applications focused on understanding the role of CA XII in various physiological and pathological processes, including cancer and metabolic disorders. Its specificity and potency make it an essential tool for studies aimed at elucidating the mechanisms of CA XII and developing potential therapeutic strategies targeting this enzyme.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 2414601-79-7 |
| Applications | CAXII Inhibitor |
| Formula | C22H27N5O6S |
| Molecular Weight | 489.54 |
| SMILES | O=C(NNC(NCC1=CC=C(OC)C=C1)=O)C2CCN(C(C3=CC=C(S(=O)(N)=O)C=C3)=O)CC2 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.