HCN2 modulator-8

Catalog No.: A68104
HCN2 Inhibitor
HCN2 modulator-8 is a selective inhibitor of the HCN2 channel, classified as a pyrazolopyridine derivative. It exhibits significant activity in modulating hyperalgesic and sensory signaling pathways, making it valuable for research into pain management, tinnitus, and various central nervous system disorders, including psychiatric and mood disorders.
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5mg
10mg
50mg
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Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionHCN2 modulator-8 is a selective inhibitor of the HCN2 channel, classified as a pyrazolopyridine derivative. It exhibits significant activity in modulating hyperalgesic and sensory signaling pathways, making it valuable for research into pain management, tinnitus, and various central nervous system disorders, including psychiatric and mood disorders.
Product Information
Catalog NumA68104
FormulaC21H18FN5O4S
Molecular Weight455.46
CAS Number3080809-12-4
SMILESO=C(C1=CC=NS1)NC2=NN(C[C@H](C)OC)C3=NC=C(C4=CC=C(OCO5)C5=C4F)C=C23
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