Fig. 1 · Structure
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HCV-IN-7 hydrochloride
HCV NS5A Inhibitor
HCV-IN-7 hydrochloride is a potent pan-genotypic inhibitor of the hepatitis C virus (HCV) NS5A protein, demonstrating IC50 values ranging from 3 to 47 pM. This compound exhibits notable anti-viral activity and advantages in pharmacokinetics, including effective liver uptake. It serves as a valuable research tool for the development of HCV therapeutics and the study of viral resistance mechanisms.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 1449756-87-9 |
| Applications | HCV NS5A Inhibitor |
| Formula | C40H50Cl2N8O6S |
| Molecular Weight | 841.85 |
| SMILES | [H]Cl.[H]Cl.O=C([C@H](C(C)C)NC(OC)=O)N(CCC1)[C@@H]1C(N2)=NC=C2C3=CC(C=C4)=C(S3)C5=C4C=C(C6=CN=C([C@H]7N(C([C@H](C(C)C)NC(OC)=O)=O)CCC7)N6)C=C5 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.