Fig. 1 · Structure
Documents & Downloads
HDAC6-IN-21
HDAC6 Inhibitor
HDAC6-IN-21 is a reversible inhibitor of histone deacetylase 6 (HDAC6), a key enzyme involved in the regulation of cellular acetylation processes. This compound demonstrates significant biological activity in modulating HDAC6-mediated pathways, making it valuable for research applications in neurodegenerative diseases and cancer biology. By inhibiting HDAC6, HDAC6-IN-21 can aid in the investigation of protein aggregation and cellular stress responses, providing insights into therapeutic potential.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 2920929-76-4 |
| Applications | HDAC6 Inhibitor |
| Formula | C14H13F2N5O2 |
| Molecular Weight | 321.28 |
| SMILES | O=C(C1=CN=C(NCC2=CC=CC=C2)N=C1)NNC(C(F)F)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.