hDDAH-1-IN-1 TFA is a selective non-amino acid inhibitor targeting human dimethylarginine dimethylaminohydrolase-1 (hDDAH-1), exhibiting a Ki of 18 μM. This compound demonstrates potent inhibition of the enzyme's catalytic activity, making it a valuable tool for studying the regulation of nitric oxide synthase and the metabolism of asymmetric dimethylarginines. Research applications include investigations into cardiovascular diseases, endothelial function, and polyamine metabolism.
hDDAH-1-IN-1 TFA is a selective non-amino acid inhibitor targeting human dimethylarginine dimethylaminohydrolase-1 (hDDAH-1), exhibiting a Ki of 18 μM. This compound demonstrates potent inhibition of the enzyme's catalytic activity, making it a valuable tool for studying the regulation of nitric oxide synthase and the metabolism of asymmetric dimethylarginines. Research applications include investigations into cardiovascular diseases, endothelial function, and polyamine metabolism.
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