hDDAH-1-IN-1 is a potent and selective inhibitor of human dimethylarginine dimethylaminohydrolase-1 (hDDAH-1), functioning through non-amino acid catalytic site inhibition, with an inhibition constant (Ki) of 18 μM. By inhibiting DDAH, this compound regulates the metabolism of asymmetric dimethylarginine (ADMA), influencing nitric oxide production. This makes hDDAH-1-IN-1 valuable in research applications related to cardiovascular diseases, neurodegenerative disorders, and conditions where nitric oxide dysregulation plays a critical role.
hDDAH-1-IN-1 is a potent and selective inhibitor of human dimethylarginine dimethylaminohydrolase-1 (hDDAH-1), functioning through non-amino acid catalytic site inhibition, with an inhibition constant (Ki) of 18 μM. By inhibiting DDAH, this compound regulates the metabolism of asymmetric dimethylarginine (ADMA), influencing nitric oxide production. This makes hDDAH-1-IN-1 valuable in research applications related to cardiovascular diseases, neurodegenerative disorders, and conditions where nitric oxide dysregulation plays a critical role.
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