Fig. 1 · Structure
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Heliotrine N-oxide
DNA Adduct Formation
Heliotrine N-oxide is a pyrrolizidine alkaloid N-oxide that facilitates the formation of pyrrolic DNA adducts. This compound is instrumental in studying PA-induced liver tumor initiation in vivo, making it valuable for cancer research and toxicology studies. Its ability to interact with DNA underscores its relevance in investigating mechanisms of genotoxicity and carcinogenesis associated with pyrrolizidine alkaloids.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 6209-65-0 |
| Applications | DNA Adduct Formation |
| Formula | C16H27NO6 |
| Molecular Weight | 329.39 |
| SMILES | [O-][N+]1(CC[C@@H]2O)[C@]2([H])C(COC([C@@](C(C)C)(O)[C@@H](C)OC)=O)=CC1 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.