Fig. 1 · Structure
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Hellebrin
Bufadienolide Compound
Hellebrin is a bufadienolide compound that primarily targets Na+/K+-ATPase, influencing intracellular signaling pathways. This compound exhibits significant anti-tumor activity by inhibiting cell growth and shows promise in overcoming apoptotic resistance in cancer cells. Additionally, Hellebrin has demonstrated anti-proliferative effects in multidrug-resistant cancer cell models, making it a valuable tool for cancer research and drug resistance studies.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 13289-18-4 |
| Applications | Bufadienolide Compound |
| Formula | C36H52O15 |
| Molecular Weight | 724.79 |
| SMILES | O=C1C=CC([C@H]2CC[C@@]3([C@@]4(CC[C@@]5(C[C@H](CC[C@@]5([C@]4(CC[C@]23C)[H])C=O)O[C@]6([C@H](O)[C@H](O)[C@@]([H])(O[C@H]7[C@H](O)[C@@H](O)[C@H](O)[C@H](O7)CO)[C@@H](O6)C)[H])O)[H])O)=CO1 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.