Fig. 1 · Structure
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Hepcidin antagonist-1
Hepcidin Antagonist
Hepcidin antagonist-1 is a potent hepcidin antagonist that demonstrates an IC50 of less than 50 μM. This compound is valuable for investigating disorders related to iron metabolism, including types of anemia. Its ability to inhibit hepcidin may provide insights into therapeutic approaches for managing iron-related diseases.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Antagonist |
| CAS Number | 338965-09-6 |
| Applications | Hepcidin Antagonist |
| Formula | C16H13Cl2N5 |
| Molecular Weight | 346.21 |
| SMILES | ClC1=C(CC2=C(N)N=C(N=C2N)C3=NC=CC=C3)C=CC(Cl)=C1 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.