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Hepoxilin A3

Neutrophil Chemo-Attractant

Hepoxilin A3 (HXA3) is a potent neutrophil chemo-attractant generated through the activation of the phospholipase A2 and lipoxygenase (PLA2-12-LOX) pathway. This compound facilitates the migration of neutrophils across epithelial barriers to sites of infection, such as the alveolar cavity. Elevated levels of Hepoxilin A3 correlate with increased neutrophil infiltration in murine models, making it a valuable tool for studying inflammatory diseases such as pneumonia and cystic fibrosis.

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Specifications

Manufacturer	Adooq Bioscience
CAS Number	94161-11-2
Applications	Neutrophil Chemo-Attractant
Formula	C₂₀H₃₂O₄
Molecular Weight	336.47
Synonyms	HXA3
SMILES	CCCCC/C=C\C[C@]1([H])O[C@@]1(/C=C/C(C/C=C\CCCC(O)=O)O)[H]

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.