Fig. 1 · Structure
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HER2-IN-12
HER2 Inhibitor
HER2-IN-12 is a potent HER2 inhibitor with an IC50 value of 121 nM. It selectively targets the HER2 receptor, making it a valuable tool in cancer research, particularly in the study and treatment of breast cancer. Its efficacy in inhibiting HER2 activity supports investigations into therapeutic strategies for HER2-positive malignancies.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 2820126-51-8 |
| Applications | HER2 Inhibitor |
| Formula | C17H18BrN5O2S |
| Molecular Weight | 436.33 |
| SMILES | O=C(C1=CSC2=NC(CN3CCOCC3)=C(C4=CC=C(Br)C=C4)N21)NN |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.