Fig. 1 · Structure

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HER2-IN-21

HER2 Inhibitor

HER2-IN-21 is a potent inhibitor of the human epidermal growth factor receptor 2 (HER2), exhibiting an IC50 value of 3.85 μM. This compound is valuable for research focusing on HER2-positive cancers, including breast and gastric cancers. HER2-IN-21 is utilized in studies aimed at understanding HER2 signaling pathways and evaluating the efficacy of targeted therapies in cancer treatments.

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Specifications

Manufacturer Adooq Bioscience
Actions Inhibitor
CAS Number 906437-59-0
Applications HER2 Inhibitor
Formula C20H18N4O3S
Molecular Weight 394.45
SMILES
COC1=CC=CC(C2SC(N)=NC3=C2C(C)=NN3C(C4=CC=CC=C4O)=O)=C1

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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