HER2-targeted peptide H6F is designed to selectively bind to the HER2 receptor, making it a valuable tool for targeting breast cancer cells. Its amino acid sequence, YLFFVFER, allows for effective conjugation with the bifunctional chelating agent hydrazinonicotinamide (HYNIC) for radiolabeling with 99mTc. Studies utilizing single-photon emission computed tomography (SPECT) demonstrate that the radiolabeled H6F peptide accumulates specifically in HER2-positive MDA-MBA-453 tumor-bearing mouse models. This peptide is applicable for tumor molecular imaging studies, aiding in the evaluation and monitoring of breast cancer.
HER2-targeted peptide H6F is designed to selectively bind to the HER2 receptor, making it a valuable tool for targeting breast cancer cells. Its amino acid sequence, YLFFVFER, allows for effective conjugation with the bifunctional chelating agent hydrazinonicotinamide (HYNIC) for radiolabeling with 99mTc. Studies utilizing single-photon emission computed tomography (SPECT) demonstrate that the radiolabeled H6F peptide accumulates specifically in HER2-positive MDA-MBA-453 tumor-bearing mouse models. This peptide is applicable for tumor molecular imaging studies, aiding in the evaluation and monitoring of breast cancer.
This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:
