Cellular Effect
| Cell Line | Activity | Value | Description | Reference |
|---|---|---|---|---|
| J774.1 | IC50 | > 100 μM | Cytotoxicity against mouse J774.1 cells after 48 hrs by alamar blue satining | [PMID: 20382538] |
Fig. 1 · Structure
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Hexamethonium Bromide
non-selective ganglionic nicotinic-receptor antagonist (nAChR) antagonist
Hexamethonium Bromide is a non-selective ganglionic nicotinic-receptor antagonist (nAChR) antagonist, with mixed competitive and noncompetitive activity.
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Biological Activity
Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Antagonist |
| CAS Number | 55-97-0 |
| Applications | non-selective ganglionic nicotinic-receptor antagonist (nAChR) antagonist |
| Formula | C12H30Br2N2 |
| Molecular Weight | 362.19 |
| SMILES | C[N+](C)(C)CCCCCC[N+](C)(C)C.[Br-].[Br-] |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.