Fig. 1 · Structure
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Hexamethylene bisacetamide
Cell Differentiation Agent
Hexamethylene bisacetamide (HMBA) is a cell differentiation agent that promotes tumor cell differentiation while inhibiting cell proliferation, demonstrating significant antitumor activity. This compound induces apoptosis through the modulation of Notch1, Bcl-2, and p53 signaling pathways. Additionally, HMBA has been shown to improve the obesity phenotype in animal models, making it a valuable tool for research in cancer and metabolic studies.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 3073-59-4 |
| Applications | Cell Differentiation Agent |
| Formula | C10H20N2O2 |
| Molecular Weight | 200.28 |
| Synonyms | HMBA |
| SMILES | CC(NCCCCCCNC(C)=O)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.