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Hexamethylphosphoramide-d18

Stable Isotope

Hexamethylphosphoramide-d18 is a deuterated form of Hexamethylphosphoramide, acting as a stable isotope for analytical research. This compound serves as a polar aprotic solvent and flame retardant while participating in metabolic processes, specifically undergoing cytochrome P-450-mediated N-demethylation to produce formaldehyde. Hexamethylphosphoramide-d18 is utilized in studies investigating DNA-protein crosslinking and its implications in carcinogenicity, particularly in relation to nasal tumors and reproductive toxicity. It provides valuable insights for researchers examining chemical toxicity and metabolic pathways.

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Specifications

Manufacturer	Adooq Bioscience
CAS Number	51219-90-0
Applications	Stable Isotope
Formula	C₆D₁₈N₃OP
Molecular Weight	197.31
SMILES	[2H]C([2H])([2H])N(C([2H])([2H])[2H])P(N(C([2H])([2H])[2H])C([2H])([2H])[2H])(N(C([2H])([2H])[2H])C([2H])([2H])[2H])=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.