Fig. 1 · Structure
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HFI-437
IRAP Inhibitor
HFI-437 is a potent non-peptidic inhibitor of insulin-regulated aminopeptidase (IRAP), exhibiting a Ki of 20 nM. This compound has been shown to enhance cognitive function, making it a valuable tool for research in the areas of neuropharmacology and cognitive disorders. Its ability to modulate aminopeptidase activity positions HFI-437 as a promising candidate for studies investigating memory and learning processes.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 1110650-74-2 |
| Applications | IRAP Inhibitor |
| Formula | C23H20N2O5 |
| Molecular Weight | 404.42 |
| SMILES | O=C(C1=C(NC(C)=O)OC2=CC(O)=CC=C2C1C3=CN=C4C=CC=CC4=C3)OCC |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.