HG-14-10-04
Catalog No.: A16267
ALK/EGFR inhibitor
HG-14-10-04 is a potent and specific ALK inhibitor with IC50 of 20 nM.
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Biological Activity
| Description | HG-14-10-04 is a potent and specific ALK inhibitor with IC50 of 20 nM. | ||
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| Targets |
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Product Information
| Catalog Num | A16267 |
|---|---|
| Formula | C29H34ClN7O |
| Molecular Weight | 532.08 |
| CAS Number | 1356962-34-9 |
| SMILES | CN1CCN(CC1)C2CCN(CC2)C3=CC(=C(C=C3)NC4=NC=C(C(=N4)C5=CNC6=CC=CC=C65)Cl)OC |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
Solubility
| In vitro | DMSO | 9 mg/mL (16.91 mM) | |
| Water | Insoluble | ||
| Ethanol | Insoluble | ||
| * <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. | |||
Preparing Stock Solutions
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 18.79 mL | 93.97 mL | 187.94 mL |
| 0.5 mM | 3.76 mL | 18.79 mL | 37.59 mL |
| 1 mM | 1.88 mL | 9.4 mL | 18.79 mL |
| 5 mM | 0.38 mL | 1.88 mL | 3.76 mL |
Useful Calculator
This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:
Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)
Please check COA/MSDS for correct molecular weight.
Calculate the dilution required to prepare a stock solution.This equation is commonly abbreviated as: C1V1 = C2V2
