Fig. 1 · Structure
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HG-7-85-01-NH2
Ligands for Target Protein for SNIPERs
HG-7-85-01-NH2 is a synthetic ligand designed for use in SNIPER (specific and potent target protein degradation) applications. This compound features the HG-7-85-01 moiety, which inhibits ABL, and is linked to an IAP ligand to facilitate targeted protein degradation. It holds potential for advancing research in targeted therapies and cellular protein regulation.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Ligand / Binder |
| CAS Number | 1258391-29-5 |
| Applications | Ligands for Target Protein for SNIPERs |
| Formula | C27H27F3N6OS |
| Molecular Weight | 540.60 |
| SMILES | O=C(NC1=CC=C(CN2CCN(CC)CC2)C(C(F)(F)F)=C1)C3=CC=CC(C4=CC=C5C(SC(N)=N5)=N4)=C3 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.