Fig. 1 · Structure
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HGF-IN-1
HGF Inhibitor
HGF-IN-1 is a specific inhibitor of hepatocyte growth factor (HGF), which plays a pivotal role in cellular processes such as proliferation, migration, and morphogenesis. This compound has demonstrated significant biological activity in inhibiting HGF-mediated signaling pathways, making it a valuable tool for cancer research. HGF-IN-1 can be utilized in studies focused on tumor growth, metastasis, and the exploration of therapeutic strategies targeting the HGF/cMET axis.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 874744-59-9 |
| Applications | HGF Inhibitor |
| Formula | C29H29F3N6O2 |
| Molecular Weight | 550.57 |
| SMILES | FC(F)(C1=CC(N2CCN(CC2)C3=NC(N4CC5=CC(OC)=C(C=C5CC4)OC)=C6C=CC=CC6=N3)=NC=C1)F |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.