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HIF-PHD-IN-4

PHD2 Inhibitor

HIF-PHD-IN-4 is a potent inhibitor of prolyl hydroxylase domain 2 (PHD2) with an IC50 of 100 nM. This compound effectively promotes the mobilization of hematopoietic stem cells in murine models when administered at a dosage of 2 mg/kg, making it a valuable tool in cancer research and therapeutic applications. HIF-PHD-IN-4 is particularly useful for studies related to tumor therapy and the modulation of the hypoxic response in cellular environments.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	3108252-48-5
Applications	PHD2 Inhibitor
Formula	C₂₀H₂₁N₅O₃
Molecular Weight	379.41
SMILES	O=C(NCC1=CC=NN=C1)C2=C(C(C=CN3C4CCCCC4)=C(C3=O)C=N2)O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.