Fig. 1 · Structure
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hIgG-hFc receptor-IN-1
hIgG–hFc Receptor Inhibitor
hIgG-hFc receptor-IN-1 functions as an inhibitor of the human immunoglobulin G-human neonatal Fc receptor (hIgG-hFcRn) protein-protein interaction, exhibiting an IC50 of 2 μM. This compound is valuable for studies exploring antibody recycling and degradation, as well as in research focused on modulating immune responses. Its role as an hFc receptor inhibitor may provide insights into therapeutic strategies for various autoimmune diseases and conditions involving abnormal antibody levels.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 1425051-22-4 |
| Applications | hIgG–hFc Receptor Inhibitor |
| Formula | C30H36N6O3 |
| Molecular Weight | 528.65 |
| SMILES | N#CC(C1=NC2=C(N=C1N3CCCCCC3)C=CC=C2)C(NC(CN4CCOCC4)C5=CC=C(C=C5)OC)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.