Fig. 1 · Structure
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Hippuric acid
Metabolite
Hippuric Acid is an orally active metabolite that results from the metabolism of polyphenols and benzoic acid by intestinal microorganisms. It exhibits biological activities such as decreasing NRF2 and MMP9 levels, leading to reactive oxygen species (ROS) accumulation. Furthermore, Hippuric Acid activates TGFβ/SMAD signaling pathways, demonstrating potential for therapeutic applications in conditions like hyperuricemia and colitis. Additionally, it serves as a valuable tool in cardiovascular disease research.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 495-69-2 |
| Applications | Metabolite |
| Formula | C9H9NO3 |
| Molecular Weight | 179.18 |
| Synonyms | Benzoylglycine |
| SMILES | O=C(O)CNC(C1=CC=CC=C1)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.